| 상엽과 상지 열수 및 에탄올 추출물의 생리활성 |
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김정숙, 김종봉 |
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| Research Paper : Biological Activities of Extracts from Mullberry (Morus alba) Leaves and Branches |
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Jung Sook Kim, Jong Bong Kim |
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| Abstract |
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Mulberry (Morus alba) leaf and branch, widely known for their use in oriental medicines, are of interest for their anti-diabetic, antihyperlipidemic, anti-oxidant, anti-inflammatory effects. This study was determined to analyze biological activities of extracts from mulberry leaves and branches. Free sugar content of extract indicated 1.598% and 1.141% of glucose in water extract from mulberry leaves and in ethanol extract from mulberry branches, respectively. In addition, analysis of free amino acids revealed that water extract from mulberry leaves contains 170.77 mg/100 g of aspartic acids while mulberry branch ethanol extract contains 85.55 mg/100 g of glutamic acids. These substances are classified as moisturizing agents in the Standards of Cosmetic Ingredients, indicating their potential use as cosmetic ingredients. The reducing power measured by anti-oxidant analysis was 2.13% for 1% mulberry leaf ethanol extract while the electron donating ability was measured at 80.97% for 0.1% mulberry leaf water extract, superoxide dismutase (SOD)-like activity at 86.6% for 1% mulberry branch ethanol extract and 62.62% for 0.5% mulberry leaf water extract. The anti-oxidant analysis produced higher measures for mulberry leaves and water extract than for mulberry branches and ethanol extract. Tyrosinase inhibitory activity, which is related to skin pigmentation, was measured at 35.46% for 0.25% mulberry leaf water extract, showing that mulberry leaf has slightly higher tyrosinase inhibitory activity than mulberry branch does. Elastase inhibitory activity, which is related to skin wrinkling, was the highest in 0.01% mulberry branch ethanol extract, at 93.7%, followed by 0.25% mulberry leaf water extract (84.03%), 0.1% mulberry leaf ethanol extract (80.12%) and 0.01% mulberry branch water extract (80.59%). According to these results, extracts from mulberry leaves and branches at low concentration produced higher values. Extracts of both mulberry leaves and branches displayed anti-oxidant and skin nourishing effects while, overall, extract from mulberry leaves was found to be higher in anti-oxidant effects and biological activity than its branch counterpart. |
| Key Words:
Mulberry, Biological activity, Anti-oxidant, Tyrosinase, Elastase |
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