Research Paper : The Effect of Cosmetic Included Purified Bee Venom on the Improvement of Skin Wrinkle

Han, Sang Mi; Hong, In Phyo; Woo, Soon Ok; Chun, Sung Nam; Han, Chung Sub

Journal of the Korean Society of Cosmetology 2015;21(2):288-292.
Published online April 30, 2015.

정제봉독을 함유한 봉독화장품의 피부주름 개선 효과

한상미, 홍인표, 우순옥, 천성남, 한충섭

Research Paper : The Effect of Cosmetic Included Purified Bee Venom on the Improvement of Skin Wrinkle

Sang Mi Han, In Phyo Hong, Soon Ok Woo, Sung Nam Chun, Chung Sub Han

Abstract

In the last few decades, there has been a substantial increase in the population of aged people. Aging skin is a common concern for many people theses days. The purpose of this study was to evaluate the efficacy of serum containing purified bee venom in reducing wrinkles. Bee venom serum was applied to the face after toner of 22 subjects twice a day for 12 weeks The changes of the skin wrinkles were analyzed with the visual grade of wrinkle and the image of the skin replica. Compared to before and after treatment, the visual grade of wrinkle was improved 11.83% after 12 weeks. The wrinkle squares and depths were significantly reduced after 12 weeks(p<0.05). Also, the wrinkle counts were significantly reduced after 12 weeks(p<0.5). Adverse reactions of subjects were not observed during the course of the study. These observations indicate that the treatment of purified bee venom seems to be effective in improving wrinkles and can be usefully tho the anti-aging cosmetic industry.

Key Words: Apis mellifera, Purified bee venom, Wrinkle, Skin