Research Paper : Preparation and Evaluation of a Cosmetic Adhesive containing Chitosan and Hypoallergenic Materials

Min, Hye Jo; Kim, Jeong Hee

Journal of the Korean Society of Cosmetology 2016;22(2):412-418.
Published online April 30, 2016.

키토산 및 저자극성 원료를 이용한 미용용 접착제 제조 및 평가

민혜조, 김정희

Research Paper : Preparation and Evaluation of a Cosmetic Adhesive containing Chitosan and Hypoallergenic Materials

Hye Jo Min, Jeong Hee Kim

Abstract

Chitosan is a high molecular weight, biodegradable natural substance. Owing to the proven safety of chitosan, it is widely used in various areas, especially in the adhesion for mucin and biodegradable. In this study, an adhesive was synthesized using a combination of chitosan and an adhesive base containing distilled water, thickener, antioxidant, silica, ethanol, and emulsifier. To evaluate the chitosan-based adhesive, it was compared to other commercially available products such as spirit gum. The chitosan-based adhesive demonstrated antimicrobial activity based on the presence of an inhibition zone. As shown by the 3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyltetrazolium bromide (MTT) cell viability assay, the chitosan-based adhesive recorded more than 80% of cell viability across the whole range of tested adhesive concentrations. Centrifuge and cycling tests confirmed that neither material separation nor a change in the physical characteristic and shape of the test sample was detected. The viscosity of the chitosan-based adhesive was higher than that of spirit gum, whereas the tensile strengths of the chitosan-based adhesive and spirit gum were 2.20

Key Words: Chitosan, Cosmetic adhesive, Hypoallergenic, Natural ingredient, Spirit gum