| 황금발효물이 고지방 식이 마우스의 혈청 및 지방간에 미치는 영향 |
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왕철, 최화정, 윤미영 |
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| Effect of Scutellaria baicalensis Georgi Fermented with Leatiporus sulphureus on Serum and Hepatic Steatosis of High-fed Diet Mice |
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zhe Wang, Hwa-jung Choi, Mi-young Yun |
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| Abstract |
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In this study, we investigated the preventive effects of the Scutellaria baicalensis Georgi fermented with Leatiporus sulphureus (SB-LS) on high-fat diet (HFD) induced body weight, food efficiency ratio (FER), liver weight, biochemical parameters of blood [total cholestrerol (TC), triglyceride (TG), glucose, creatinine, free fatty acid (FFA), aspartate aminotransferase (GOT) and alanine aminotransferase (GPT)] and hepatic steatosis in mice. The SB-LS were supplemented with HFD at 300 mg/kg dosage for 10 weeks. The administration of HFD/SB-LS was recovered body weight gain, FER, biochemical parameters of blood (TC, glucose, TG, creatinine, FFA, GOT and GPT) into normal levels. In addition, histopathological analyses of liver tissues revealed a decrease of hepatic steatosis in hepatocytes in the HFD/SB-LS groups. These results suggest that SB-LS can reduce the development of obesity, metabolic disorders and hepatic steatosis. |
| Key Words:
Biochemical parameters, Hepatic steatosis, High-fat diet, Leatiporus sulphureus, Scutellaria baicalensis |
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