Journal of the Korean Society of Cosmetology 2018;24(5):1014-1020.
Published online October 31, 2018.
삼칠근 열수추출물의 항산화 및 항염 활성 연구
왕이연, 김은숙, 이지안
The study of Antioxidant and Anti-inflammatory Effects of Notoginseng Root (NGR) Hot Water Extracts
Yi-ran Wang, Eun Sook Kim, Ji-an Lee
Abstract
This study examined the antioxidant and anti-inflammatory activity of Notoginseng Root (NGR) hot water extracts to develop a cosmetics material using natural plant resources. Antioxidant effects were evaluated based on DPPH and ABTS radical scavenging activity and total polyphenol contents. In addition, anti-inflammatory effects were measured using MTT assay, nitric oxide (NO) colorimetric assay, western blot analysis, enzyme-linked immunosorbent assay (ELISA) and real-time polymerase chain reaction (real-time PCR). The DPPH electron donating and ABTS radical scavenging activities increased significantly in a dose-dependent manner. The measured total polyphenol content of NGR hot water extracts was 2.8
Key Words: Anti-inflammatory activity, Antioxidant activity, Cosmeceutical, Notoginseng root, Real-time PCR


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