The study of Antioxidant and Anti-inflammatory Effects of Notoginseng Root (NGR) Hot Water Extracts

Wang, Yi-ran; Kim, Eun Sook; Lee, Ji-an

Journal of the Korean Society of Cosmetology 2018;24(5):1014-1020.
Published online October 31, 2018.

삼칠근 열수추출물의 항산화 및 항염 활성 연구

왕이연, 김은숙, 이지안

The study of Antioxidant and Anti-inflammatory Effects of Notoginseng Root (NGR) Hot Water Extracts

Yi-ran Wang, Eun Sook Kim, Ji-an Lee

Abstract

This study examined the antioxidant and anti-inflammatory activity of Notoginseng Root (NGR) hot water extracts to develop a cosmetics material using natural plant resources. Antioxidant effects were evaluated based on DPPH and ABTS radical scavenging activity and total polyphenol contents. In addition, anti-inflammatory effects were measured using MTT assay, nitric oxide (NO) colorimetric assay, western blot analysis, enzyme-linked immunosorbent assay (ELISA) and real-time polymerase chain reaction (real-time PCR). The DPPH electron donating and ABTS radical scavenging activities increased significantly in a dose-dependent manner. The measured total polyphenol content of NGR hot water extracts was 2.8

Key Words: Anti-inflammatory activity, Antioxidant activity, Cosmeceutical, Notoginseng root, Real-time PCR