| 마황복합추출물이 고지방식이로 유발된 비만생쥐의 혈청지질 및 조직학적 변화에 미치는 영향 |
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신진기, 최정숙, 백경연 |
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| Effect of Mahangbokhap Extract Lipid Profile and Tissue in HFD-induced Obese Mice |
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Jin Gi Shin, Jung Sook Choi, Gyung Yun Beik |
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| Abstract |
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This study was conducted by histopathology and histomorphology to examined that anti-obesity effects of mixed water extract of Mahwangbokhap on liver and epididymal fat tissues in obese mice with high-fat diet. The extracts of Mahwangbokhap were significantly inhibited the body weight gain of obese mice induced by high fat diet. In addition, liver weight, fat around the epididymal, and fat around the kidney were significantly reduced. Serum lipids such as Total cholesterol, LDL-cholesteol and Total lipid were significantly decreased in the high-fat diet, but the serum adiponectin level was significantly increased. Glucose and insulin levels in obese mice induced by high-fat diet were significantly reduced. As a result, It was suggested that the extract of Mahwangbokhap extract is effective for improving obesity in obese mice induced by high-fat diet. It significantly compo sition, It is considered safe to use. M |
| Key Words:
Body fat reduction, High fat diet, Mahangbokhap extract, Obesity |
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