Journal of the Korean Society of Cosmetology 2019;25(1):156-161.
Published online February 28, 2019.
B16F10 세포에서 연두털말 에탄올 추출물의 멜라닌 생성 저해효과
박서경, 정유헌, 박종군, 김수정, 정대현, 최한길
Inhibitory Effects of Papenfusiella kuromo Ethanol Extracts on Melanin Formation in B16F10 Murine Melanoma Cells
Seo Kyoung Park, Yu Heon Chung, Jong Kun Park, Su Jung Kim, Dai Hyun Jung, Han Gil Choi
Abstract
To test the possibility of natural cosmetic material, the antioxidant activity using DPPH method and whitening effect for the ethanol extract of a brown alga, Papenfusiella kuromo were examined. In particular whitening effects were estimated by melanin production of B16F10 melanoma cells and confirmed by tyrosinase gene expression in terms of RT-PCR and western bolt analyses. Present results revealed that DPPH radical scavenging activity for P. kuromo extract was about 64% at 50
Key Words: B16F10 cell, DPPH, Melanin, Papenfusiella kuromo, Tyrosinase


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