Journal of the Korean Society of Cosmetology 2007;13(3):1366-1375.
C57BL / 6 마우스 모델에서 복합 한약추출물의 모발성장 촉진효과
형순희, 강성례, 김영철
Research Papaer : Effect of Complex Oriental Medicine Extract on Hair Growth Promotion in An Alopecia Model of C57BL / 6 Mice
Soon Hee Hyung, Sung Rye Gang, Young Chul Kim
Abstract
This study was carried out to evaluate the effect of complex oriental medicine extract on hair growth promotion in an alopecia model of C57BL / 6 mice. Six weeks old male mice were divided into four groups including normal group(saline), vehicle control group(ethanol+jojoba oil+water), positive control group(3% minoxidil) and experimental group(complex oriental medicine extract mixed in vehicle). And they were applied topically with test compounds for 3 weeks. Hair regrowth effect in experimental group using gross and histological examination was similar to that in positive control group, average of approximately 40%. Body weight gain and hematological values for experimental group were not significantly different from those for normal group. These results indicated that the extract of complex oriental medicine can be used practically for hair growth or prevention of hair loss.
Key Words: C57BL / 6 Mouse, Oriental Medicine, Hair Growth, Hair Follicle


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