세포독성과 형태학적 변화 관찰을 통한 5종 에센셜 오일의 안전성 검색 |
윤영한, 김경순, 오혜영, 유병수, 김기영 |
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Research Paper : A Screening of 5 Species Essential Oil`s Safety by the Observation of Cytotoxicity and Morphological Change on Cells |
Young Han Yun, Kyong Soon Kim, Hye Young Oh, Byong Soo Yu, Ki Young Kim |
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Abstract |
In medical- and esthetic area the aromatherapy has spread widely by using of inhalation, bath and topical massage with essential oil. Thereby the safety, danger of irritation and sensitive reaction and injury of essential oil must be considered for clients and therapists. Therefore, in this study the safety of 5 species essential oils (ginger, cypress, rosemary, lavender and black pepper) was proven by the measurement of MTT-assay and sirius red staining. Liver cell, brain cell and kidney cell were chosen for the cell viability assay and morphological change observations. In this result, ginger and rosemary have shown as 50% of liver cell viability in concentration of 0.0012 |
Key Words:
MTT-Assay, Essential Oil, Cytotoxicity, Ginger, Rosemary, Lavender, Black Pepper |
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