Research Paper : Effects of Walnut Extracts on cytokines in Mice Spleen with DNCB-induced Dermatitis

Yoon, Mi Sook

Journal of the Korean Society of Cosmetology 2009;15(3):1033-1040.
Published online September 30, 2009.

DNCB-유도 아토피 피부염의 mouse 비장(spleen)에서 cytokine 활성에 대한 호두추출물의 영향

윤미숙

Research Paper : Effects of Walnut Extracts on cytokines in Mice Spleen with DNCB-induced Dermatitis

Mi Sook Yoon

Abstract

It has been strongly suggested that atopic dermatitis is due to an epiphenomena of immunologic aberrations, distinctively to a genetically predisposed population. Especially, this expression of polygenic and phenotypic immunologic aberrations, with the potential for producing a spectrum of inflammatory reactions, would be initiated by the cytokinal profile altered by Th2(helper type-2 T cell)/Th1(helper type-1 T cell) unbalance. Th1-mediated cytokine, such as IFN-

Key Words: Atopic Dermatitis, IFN-γ, IL-4, T Cell, Walnut Extracts

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