| Streptococcus thermophilus로 발효된 백년초 발효물의 피부생리활성 평가 |
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최화정, 정주임 |
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| Evaluation of Dermal Bioactive Properties of Opuntia humifusa (Backryeoncho) Fruits Fermented with Streptococcus thermophilus |
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Hwa Jung Choi, Jung Ju Im |
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| Abstract |
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To identify materials possessing adermal bioactive properties, this study was conducted the effects of Opuntia ficusindica fruits fermented with Steptococcus thermophilus (OFST) on cytotoxicity of human dermal fibroblast, antioxidant activity, collagen biosynthesis and matrix metalloproteinase-I (MMP-1) activity. As the results, the number of viable bacteria for OFST after fermentation for 12 h showed 0.4 log CFU/mL and it exhibited 8 log CFU/mL after fermentation for 24 h. The initial pH of OFST was 7.2. The pH between 12-24 h was 6.4 and 4.7, respectively, The pH of OFST after fermentation for 24 h was 4.5. The OFST didn`t show cytotoxicity against human dermal fibroblast at tested concentration. The OFST didn`t show cytotoxicity against human dermal fibroblast at concentration of 1-100 |
| Key Words:
Collagen biosynthesis, Dermal bioactive materials, Matrix metalloproteinase-I, Opuntia ficusindica, Steptococcus thermophilus |
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