큰금계국 추출물의 항염증 및 피부생리활성 효과 |
서승희, 이환, 최미옥 |
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The Anti-inflammatory Actions and Dermal Bioactive Effects of Coreopsis lanceolata extracts |
Seung-hee Seo, Hwan Lee, Mee-ok Choi |
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Abstract |
This study was to investigate the possibility of the use of the extract of Coreopsis lanceolata L. on the anti-oxidant, keratinocyte protective, and anti-inflammatory activities as a safer and healthier cosmetic material. The total phenolic content of the extract of C. lanceolata increased in the concentration-dependent manners. it also has the antioxidant activities including DPPH radical scavenging activity, ABTS scavenging activity and SOD-like scavenging activity were similar to those of the positive control group. The protective effect of the extract of C. lanceolata on the human keratinocyte HaCaT showed that H2O2-induced cell damage was significantly inhibited. In addition, the extract of C. lanceolata significantly suppressed the LPS-induced nitrite, PGE2, TNF- |
Key Words:
Anti-inflammation, Anti-oxidant, Coreopsis lanceolata, Human keratinocyte HaCaT cell, RAW264.7 cell |
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