| B16F10 세포에서 연두털말 에탄올 추출물의 멜라닌 생성 저해효과 |
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박서경, 정유헌, 박종군, 김수정, 정대현, 최한길 |
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| Inhibitory Effects of Papenfusiella kuromo Ethanol Extracts on Melanin Formation in B16F10 Murine Melanoma Cells |
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Seo Kyoung Park, Yu Heon Chung, Jong Kun Park, Su Jung Kim, Dai Hyun Jung, Han Gil Choi |
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| Abstract |
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To test the possibility of natural cosmetic material, the antioxidant activity using DPPH method and whitening effect for the ethanol extract of a brown alga, Papenfusiella kuromo were examined. In particular whitening effects were estimated by melanin production of B16F10 melanoma cells and confirmed by tyrosinase gene expression in terms of RT-PCR and western bolt analyses. Present results revealed that DPPH radical scavenging activity for P. kuromo extract was about 64% at 50 |
| Key Words:
B16F10 cell, DPPH, Melanin, Papenfusiella kuromo, Tyrosinase |
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