| 천연복합물(상황버섯, 감초, 병풀)의 항산화 및 세포독성에 관한 연구 |
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김영훈, 이창언, 김병소 |
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| Research Paper : Study on Cytotoxicity Test and Anti-oxidant Activity of Herb Complex(Phellinus Linteus, Glycyrrhiza uralensis Fischer and Centella asiatica) |
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Young Hun Kim, Chang Eon Lee, Byung So Kim |
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| Abstract |
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The aim of the study was to assess the anti-oxidant activity and cell proliferation of herb complex (Phellinus linteus, Glycyrrhiza uralensis Fischer and Centella asiatica) and it is possible that can be used as a cosmetic ingredient for application of cosmetic industries. The anti-oxidant activity was determined by using DPPH radical inhibition activity, superoxide dismutase (SOD)-like activity, ABTS radical inhibition activity, hydrogen peroxide inhibition activity. In the antioxidant activities, DPPH radical inhibition activity test of herb complex showed over 80% at 100 ppm concentration and similar to BHA as a positive control at over 50 ppm. The result of SOD-like activity showed 65% at 500 ppm concentration. In the test of ABTS radical inhibition activity, herb complex showed over 80% at 50 ppm concentration. The results of cell viability assay showed that the extracts from herb complex were not cytotoxic at concentration below 1,000 ppm. Hydrogen peroxide inhibition activity of herb complex was 60% at 100 ppm concentration. It was higher then that of ascorbic acid. In this study, anti-oxidant activity and cell proliferation of herb complex were confirmed to investigate for utilization as a cosmetic ingredients. |
| Key Words:
Phellinus Linteus, Glycyrrhiza uralensis fischer, Centella asiatica, Herb complex, Anti-oxidant activity |
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