Research Paper : Effect of Ethanol Extract of Ceramium kondoi on Hypopigmentation and Antioxidant Activity

Park, Seol A; Ko, Kyoung Sook; Woo, Won Hong; Mun, Yeun Ja

Journal of the Korean Society of Cosmetology 2015;21(6):1165-1172.
Published online December 31, 2015.

비단풀 에탄올추출물의 멜라닌 합성 억제 및 항산화 효과

박설아, 고경숙, 우원홍, 문연자

Research Paper : Effect of Ethanol Extract of Ceramium kondoi on Hypopigmentation and Antioxidant Activity

Seol A Park, Kyoung Sook Ko, Won Hong Woo, Yeun Ja Mun

Abstract

This study was performed to investigate the antioxidant activities and the melanin synthesis inhibitory effects of Ceramium kondoi extracts. Ceramium kondoi was extracted with 100% ethanol. The anti-oxidative and whitening effects of extracts were determined by in vitro assays using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) method and inhibitory effects of the Ceramium kondoi extract against collagenase and tyrosinase in B16F10 melanoma cells. The results have been revealed that Ceramium kondoi extract significantly reduced intracellular tyrosinase activity and melanin synthesis in B16F10 cell. Furthermore, decreased the expression of melanogenic enzymes in B16F10 cells. Additionally, Ceramium kondoi inhibited the

Key Words: Ceramium kondoi, Tyrosinase, Melanin, Melanogenesis, Anti-oxidative