망고 잎 생리활성 물질의 항산화 효과 |
구태규, 유일수, 박안나 |
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Antioxidant Effects of Bioactive Mango Leavesa |
Tae Kyu Ku, Il Sou Yoo, An Na Park |
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Abstract |
In this study was to examine the applicability of mango (MangiferaindicaL.) leaf extract to cosmetics a composition based on its antioxidant activity. Extracted with ethanol and water to obtain a 50% concentration of mango leaf extract (0.4, 2, 10, 50 mg/ml) as mango leaf collected in Jeju Island, Korea. In 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical assay, lower concentrations of mango leaf extract resulted in a dose-dependent increase in antioxidant activity compared to the synthetic antioxidant butylated hydroxytoluene (BHT). Total polyphenol and flavonoid contents were highest in the 50 mg/mL mango leaf extract. Cell viability and cytotoxicity were assessed in RAW 264.7 cells by ROS production, macrophages were exposed to various concentrations (10, 25, and 50 |
Key Words:
Antioxidant cosmetics, DPPH, 1, 1-diphenyl-2-picrylhydrazyl, Mango leaves, ROS, Reactive oxygen species |
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