오배자의 항산화활성 및 B16 Melanoma cell을 통한 멜라닌 생성 억제능에 관한 연구 |
김경영, 허선정, 박은영, 장아름, 양기숙, 황완균 |
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Research Paper : Effects of Galla Rhois Extracts and Fractions on Anti-oxidative Acitivity and Inhibition of Melanin Synthesis by Melanoma Cell |
Kyoung Young Kim, Sun Jung Hur, Eun Young Park, A Reum Jang, Ki Sook Yang, Wan Kyun Whang |
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Abstract |
To search for new skin-lighting agents, the inhibitory property of Galla Rhois Extracts and Fractions on melanogenesis was investigated. The inhibitory action of Galla Rhois Extracts and Fractions on mushroom tyrosinase was revealed. To explore the action of Galla Rhois Extracts and Fractions on melanogenesis, the inhibition of tyrosinase and melanin contents were measured in B16F10 melanoma cells. Results show that ethylacetate fraction of Galla Rhois has strong antioxidative activity and inhibited tyrosinase activity. Also ethylacetate fraction of Galla Rhois reduced melanin contents in B16F10cells. Therefore, this data indicate Galla Rhois as a potential pigmentation reagents. |
Key Words:
Galla Rhois, Antioxidant, Tyrosinase, Melanoma Cell |
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