| 화장품 소재로서 홍삼식이뇨(尿)의 세포 생리 활성 효능연구 |
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문연숙, 강상모 |
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| Studies on the Cellular Physiological Activity of Red Ginseng Ingested Urine as a Cosmetic Material |
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Yeon-sook Moon, Sang-mo Kang |
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| Abstract |
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In this study, the cell experiments were carried out using heated urine (obtained through heat treatment of normal urine to remove microbes) and heated urine containing red ginseng (obtained through heat treatment of urine after taking red ginseng extract to increase functionality) in order to use urine as cosmetic material. RAW 264.7 macrophage, B16F10 melanoma, and CCD-986sk fibroblast were used to measure cytotoxicity of each urine sample, and toxicity for skin cells in each urine sample was hardly found. From the result of having measured the inhibitory rate of ROS production in the cells through DCF-DA, it was observed that the inhibitory effect of ROS production in each urine sample was the highest in heated urine containing red ginseng, followed by heated urine and then normal urine. From the result of having measured the anti-inflammatory effect in each urine sample using RAW 264.7 macrophage cell, it was found that the inhibitory effect of NO production (which inhibits the melanin biosynthesis in the B16F10 melanoma cells of each urine sample) was the highest in heated urine containing red ginseng, followed by heated urine and then normal urine. From the result of having measured the level of MMP-1 of CCD-986sk fibroblast cells in each urine sample, it was observed that heated urine containing red ginseng had a significant decrease (61,25%(p<0.01)) in the expression level of MMP-1 at a concentration of 5 |
| Key Words:
Anti-ageing, Anti-inflammatory, Compound K, Cosmetic, Red ginseng, Urine |
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